Publications

Publications are a key productivity measure and give a sense of the capabilites of the Facilty. This page is intended to document the depth and breadth of the work that has been done at the Facility.

Breakdown by:

Year Lab Journal

A complete list of papers describing work that made use of the Facility appears below.

    2007

  1. Allen SJ, Zabel BA, Kirkpatrick J, Butcher EC, Nietlispach D, Handel TM
    NMR assignment of human chemerin, a novel chemoattractant.
    Biomol NMR Assign. 2007 Dec;1(2):171-3

    2. 2009

  2. Hughes CC, MacMillan JB, Gaudêncio SP, Jensen PR, Fenical W
    The ammosamides: structures of cell cycle modulators from a marine-derived Streptomyces species.
    Angew Chem Int Ed Engl. 2009;48(4):725-7

  3. Winter JM, Jansma AL, Handel TM, Moore BS
    Formation of the pyridazine natural product azamerone by biosynthetic rearrangement of an aryl diazoketone.
    Angew Chem Int Ed Engl. 2009 Jan 12;48(4):767-70

  4. Morinaka BI, Pawlik JR, Molinski TF
    Amaroxocanes A and B: sulfated dimeric sterols defend the Caribbean coral reef sponge Phorbas amaranthus from fish predators.
    J Nat Prod. 2009 Feb 27;72(2):259-64

  5. Dalisay DS, Rogers EW, Edison AS, Molinski TF.
    Structure elucidation at the nanomole scale. 1. Trisoxazole macrolides and thiazole-containing cyclic peptides from the nudibranch Hexabranchus sanguineus.
    J Nat Prod. 2009 Apr;72(4):732-8

  6. Dalisay DS, Molinski TF
    NMR quantitation of natural products at the nanomole scale.
    J Nat Prod. 2009 Apr;72(4):739-44.

  7. Dalisay DS, Molinski TF
    Structure elucidation at the nanomole scale. 2. Hemi-phorboxazole A from Phorbas sp.
    Org Lett. 2009 May 7;11(9):1967-70

  8. Dalisay DS, Morinaka BI, Skepper CK, Molinski TF.
    A tetrachloro polyketide hexahydro-1H-isoindolone, muironolide A, from the marine sponge Phorbas sp. natural products at the nanomole scale.
    J Am Chem Soc. 2009 Jun 10;131(22):7552-3

  9. Pereira A, Cao Z, Murray TF, Gerwick WH
    Hoiamide a, a sodium channel activator of unusual architecture from a consortium of two papua new Guinea cyanobacteria.
    Chem Biol. 2009 Aug 28;16(8):893-906

  10. Soria-Mercado IE, Pereira A, Cao Z, Murray TF, Gerwick WH
    Alotamide A, a novel neuropharmacological agent from the marine cyanobacterium Lyngbya bouillonii.
    Org Lett. 2009 Oct 15;11(20):4704-7

    11. 2010

  11. Pereira AR, McCue CF, Gerwick WH
    Cyanolide A, a glycosidic macrolide with potent Molluscicidal activity from the Papua New Guinea cyanobacterium Lyngbya bouillonii.
    J Nat Prod. 2010 Feb 26;73(2):217-20

  12. Pereira AR, Byrum T, Shibuya GM, Vanderwal CD, Gerwick WH
    Structure revision and absolute configuration of malhamensilipin A from the freshwater chrysophyte Poterioochromonas malhamensis.
    J Nat Prod. 2010 Feb 26;73(2):279-83

  13. Schultz AW, Lewis CA, Luzung MR, Baran PS, Moore BS
    Functional characterization of the cyclomarin/cyclomarazine prenyltransferase CymD directs the biosynthesis of unnatural cyclic peptides.
    J Nat Prod. 2010 Mar 26;73(3):373-7

  14. Wang YG, Morinaka BI, Reyes JC, Wolff JJ, Romo D, Molinski TF
    Synthesis of 7-(15)N-Oroidin and evaluation of utility for biosynthetic studies of pyrrole-imidazole alkaloids by microscale (1)H-(15)N HSQC and FTMS.
    J Nat Prod. 2010 Mar 26;73(3):428-34

  15. Choi H, Engene N, Smith JE, Preskitt LB, Gerwick WH
    Crossbyanols A-D, toxic brominated polyphenyl ethers from the Hawai'ian bloom-forming Cyanobacterium Leptolyngbya crossbyana.
    J Nat Prod. 2010 Apr 23;73(4):517-22

  16. Dalisay DS, Molinski TF
    Structure elucidation at the nanomole scale. 3. Phorbasides G-I from Phorbas sp.
    J Nat Prod. 2010 Apr 23;73(4):679-82

  17. Guttman M, Prieto JH, Handel TM, Domaille PJ, Komives EA
    Structure of the minimal interface between ApoE and LRP.
    J Mol Biol. 2010 Apr 30;398(2):306-19

  18. Jansma AL, Kirkpatrick JP, Hsu AR, Handel TM, Nietlispach D
    NMR analysis of the structure, dynamics, and unique oligomerization properties of the chemokine CCL27.
    J Biol Chem. 2010 May 7;285(19):14424-37. doi: 10.1074/jbc.M109.091108. Epub 2010 Mar 3. PMID: 20200157

  19. Severin IC, Gaudry JP, Johnson Z, Kungl A, Jansma A, Gesslbauer B, Mulloy B, Power C, Proudfoot AE, Handel T
    Characterization of the chemokine CXCL11-heparin interaction suggests two different affinities for glycosaminoglycans.
    J Biol Chem. 2010 Jun 4;285(23):17713-24

  20. Choi H, Pereira AR, Cao Z, Shuman CF, Engene N, Byrum T, Matainaho T, Murray TF, Mangoni A, Gerwick WH
    The hoiamides, structurally intriguing neurotoxic lipopeptides from Papua New Guinea marine cyanobacteria.
    J Nat Prod. 2010 Aug 27;73(8):1411-21

  21. Pereira AR, Cao Z, Engene N, Soria-Mercado IE, Murray TF, Gerwick WH
    Palmyrolide A, an unusually stabilized neuroactive macrolide from Palmyra Atoll cyanobacteria.
    Org Lett. 2010 Oct 15;12(20):4490-3

    22. 2011

  22. Molinski TF, Ko J, Reynolds KA, Lievens SC, Skarda KR
    N,N'-methyleno-didemnin A from the ascidian Trididemnum solidum. Complete NMR assignments and confirmation of the imidazolidinone ring by strategic analysis of 1J(CH).
    J Nat Prod. 2011 Apr 25;74(4):882-7

  23. Mevers E, Liu WT, Engene N, Mohimani H, Byrum T, Pevzner PA, Dorrestein PC, Spadafora C, Gerwick WH
    Cytotoxic veraguamides, alkynyl bromide-containing cyclic depsipeptides from the marine cyanobacterium cf. Oscillatoria margaritifera.
    J Nat Prod. 2011 May 27;74(5):928-36

  24. Pereira AR, Etzbach L, Engene N, Müller R, Gerwick WH
    Molluscicidal metabolites from an assemblage of Palmyra Atoll cyanobacteria.
    J Nat Prod. 2011 May 27;74(5):1175-81

  25. Engene N, Choi H, Esquenazi E, Byrum T, Villa FA, Cao Z, Murray TF, Dorrestein PC, Gerwick L, Gerwick WH
    Phylogeny-guided isolation of ethyl tumonoate A from the marine cyanobacterium cf. Oscillatoria margaritifera.
    J Nat Prod. 2011 Aug 26;74(8):1737-43

  26. Miyanaga A, Janso JE, McDonald L, He M, Liu H, Barbieri L, Eustáquio AS, Fielding EN, Carter GT, Jensen PR, Feng X, Leighton M, Koehn FE, Moore BS
    Discovery and assembly-line biosynthesis of the lymphostin pyrroloquinoline alkaloid family of mTOR inhibitors in Salinispora bacteria.
    J Am Chem Soc. 2011 Aug 31;133(34):13311-3

  27. Gutiérrez M, Pereira AR, Debonsi HM, Ligresti A, Di Marzo V, Gerwick WH
    Cannabinomimetic lipid from a marine cyanobacterium.
    J Nat Prod. 2011 Oct 28;74(10):2313-7

  28. Morinaka BI, Molinski TF
    Mollenyne A, a long-chain chlorodibromohydrin amide from the sponge Spirastrella mollis.
    Org Lett. 2011 Dec 16;13(24):6338-41

    29. 2012

  29. Choi H, Proteau PJ, Byrum T, Pereira AR, Gerwick WH
    Cymatherelactone and cymatherols A-C, polycyclic oxylipins from the marine brown alga Cymathere triplicata.
    Phytochemistry. 2012 Jan;73(1):134-41

  30. Pereira AR, Kale AJ, Fenley AT, Byrum T, Debonsi HM, Gilson MK, Valeriote FA, Moore BS, Gerwick WH
    The carmaphycins: new proteasome inhibitors exhibiting an α,β-epoxyketone warhead from a marine cyanobacterium.
    Chembiochem. 2012 Apr 16;13(6):810-7

  31. Nunnery JK, Engene N, Byrum T, Cao Z, Jabba SV, Pereira AR, Matainaho T, Murray TF, Gerwick WH
    Biosynthetically intriguing chlorinated lipophilic metabolites from geographically distant tropical marine cyanobacteria.
    J Org Chem. 2012 May 4;77(9):4198-208

  32. Stout EP, Wang YG, Romo D, Molinski TF.
    Pyrrole aminoimidazole alkaloid metabiosynthesis with marine sponges Agelas conifera and Stylissa caribica.
    Angew Chem Int Ed Engl. 2012 May 14;51(20):4877-81

  33. Fuglestad B, Gasper PM, Tonelli M, McCammon JA, Markwick PR, Komives EA.
    The dynamic structure of thrombin in solution.
    Biophys J. 2012 Jul 3;103(1):79-88

  34. Moree WJ, Phelan VV, Wu CH, Bandeira N, Cornett DS, Duggan BM, Dorrestein PC.
    Interkingdom metabolic transformations captured by microbial imaging mass spectrometry.
    Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13811-6

  35. Choi H, Mevers E, Byrum T, Valeriote FA, Gerwick WH.
    Lyngbyabellins K-N from Two Palmyra Atoll Collections of the Marine Cyanobacterium Moorea bouillonii.
    European J Org Chem. 2012 Sep 1;2012(27):5141-5150

    36. 2013

  36. Radić Z, Dale T, Kovarik Z, Berend S, Garcia E, Zhang L, Amitai G, Green C, Radić B, Duggan BM, Ajami D, Rebek J, Taylor P.
    Catalytic detoxification of nerve agent and pesticide organophosphates by butyrylcholinesterase assisted with non-pyridinium oximes.
    Biochem J. 2013 Feb 15;450(1):231-42

  37. Molinski TF, Biegelmeyer R, Stout EP, Wang X, Frota ML Jr, Henriques AT
    Halisphingosines A and B, modified sphingoid bases from Haliclona tubifera. Assignment of configuration by circular dichroism and van't Hoff's principle of optical superposition.
    J Nat Prod. 2013 Mar 22;76(3):374-81

  38. Watrous JD, Phelan VV, Hsu CC, Moree WJ, Duggan BM, Alexandrov T, Dorrestein PC
    Microbial metabolic exchange in 3D.
    ISME J. 2013 Apr;7(4):770-80

  39. Januar LA, Molinski TF
    Acremolin from Acremonium strictum is N(2),3-etheno-2'-isopropyl-1-methylguanine, not a 1H-azirine. Synthesis and structural revision.
    Org Lett. 2013 May 17;15(10):2370-3

  40. de Gracia Lux C, Almutairi A
    Intramolecular Cyclization for Stimuli-Controlled Depolymerization of Polycaprolactone Particles Leading to Disassembly and Payload Release.
    ACS Macro Lett. 2013 May 21;2(5):432-435.

  41. Kersten RD, Lane AL, Nett M, Richter TK, Duggan BM, Dorrestein PC, Moore BS
    Bioactivity-guided genome mining reveals the lomaiviticin biosynthetic gene cluster in Salinispora tropica.
    Chembiochem. 2013 May 27;14(8):955-62

  42. Nguyen DD, Wu CH, Moree WJ, Lamsa A, Medema MH, Zhao X, Gavilan RG, Aparicio M, Atencio L, Jackson C, Ballesteros J, Sanchez J, Watrous JD, Phelan VV, van de Wiel C, Kersten RD, Mehnaz S, De Mot R, Shank EA, Charusanti P, Nagarajan H, Duggan BM, Moore BS, Bandeira N, Palsson BØ, Pogliano K, Gutiérrez M, Dorrestein PC
    MS/MS networking guided analysis of molecule and gene cluster families.
    Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):E2611-20

  43. Jang KH, Nam SJ, Locke JB, Kauffman CA, Beatty DS, Paul LA, Fenical W.
    Anthracimycin, a potent anthrax antibiotic from a marine-derived actinomycete.
    Angew Chem Int Ed Engl. 2013 Jul 22;52(30):7822-4

  44. Olejniczak J, Sankaranarayanan J, Viger ML, Almutairi A
    Highest Efficiency Two-Photon Degradable Copolymer for Remote Controlled Release.
    ACS Macro Lett. 2013 Aug 20;2(8):683-687.

  45. Suarez S, Grover GN, Braden RL, Christman KL, Almutairi A
    Tunable protein release from acetalated dextran microparticles: a platform for delivery of protein therapeutics to the heart post-MI.
    Biomacromolecules. 2013 Nov 11;14(11):3927-35.

  46. Kersten RD, Ziemert N, Gonzalez DJ, Duggan BM, Nizet V, Dorrestein PC, Moore BS
    Glycogenomics as a mass spectrometry-guided genome-mining method for microbial glycosylated molecules.
    Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):E4407-16

  47. Mantovani SM, Moore BS
    Flavin-linked oxidase catalyzes pyrrolizine formation of dichloropyrrole-containing polyketide extender unit in chlorizidine A.
    J Am Chem Soc. 2013 Dec 4;135(48):18032-5.

  48. Lux J, Chan M, Elst LV, Schopf E, Mahmoud E, Laurent S, Almutairi A
    Metal Chelating Crosslinkers Form Nanogels with High Chelation Stability.
    J Mater Chem B Mater Biol Med. 2013 Dec 14;1(46):6359-6364.

    49. 2014

  49. Liu WT, Lamsa A, Wong WR, Boudreau PD, Kersten R, Peng Y, Moree WJ, Duggan BM, Moore BS, Gerwick WH, Linington RG, Pogliano K, Dorrestein PC
    MS/MS-based networking and peptidogenomics guided genome mining revealed the stenothricin gene cluster in Streptomyces roseosporus.
    J Antibiot (Tokyo). 2014 Jan;67(1):99-104

  50. Farnaes L, Coufal NG, Kauffman CA, Rheingold AL, DiPasquale AG, Jensen PR, Fenical W
    Napyradiomycin derivatives, produced by a marine-derived actinomycete, illustrate cytotoxicity by induction of apoptosis.
    J Nat Prod. 2014 Jan 24;77(1):15-21

  51. Yamanaka K, Reynolds KA, Kersten RD, Ryan KS, Gonzalez DJ, Nizet V, Dorrestein PC, Moore BS
    Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A.
    Proc Natl Acad Sci U S A. 2014 Feb 4; 111(5), pp 1957-62

  52. Wang X, Morinaka BI, Molinski TF
    Structures and Solution Conformational Dynamics of Stylissamides G and H from the Bahamian Sponge Stylissa caribica.
    J Nat Prod. 2014 Mar 28;77(3):625-30

  53. Mevers E, Haeckl FP, Boudreau PD, Byrum T, Dorrestein PC, Valeriote FA, Gerwick WH
    Lipopeptides from the Tropical Marine Cyanobacterium Symploca sp.
    J Nat Prod. 2014 Apr 25;77(4):969-75

  54. Trivella DB, Pereira AR, Stein ML, Kasai Y, Byrum T, Valeriote FA, Tantillo DJ, Groll M, Gerwick WH, Moore BS.
    Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor.
    Chem Biol. 2014 Jun 19;21(6):782-91

  55. Stout EP, Choi MY, Castro JE, Molinski TF
    Potent fluorinated agelastatin analogues for chronic lymphocytic leukemia: design, synthesis, and pharmacokinetic studies.
    J Med Chem. 2014 Jun 26;57(12):5085–5093

  56. Kaczanowska K, Harel M, Radić Z, Changeux JP, Finn MG, Taylor P
    Structural basis for cooperative interactions of substituted 2-aminopyrimidines with the acetylcholine binding protein.
    Proc Natl Acad Sci USA. 2014 Jul 22;111(29):10749-54

  57. Agarwal V, El Gamal AA, Yamanaka K, Poth D, Kersten RD, Schorn M, Allen EE, Moore BS
    Biosynthesis of polybrominated aromatic organic compounds by marine bacteria.
    Nat Chem Biol. 2014 Aug;10(8):640-7

  58. Agarwal V, Moore BS
    Enzymatic Synthesis of Polybrominated Dioxins from the Marine Environment.
    ACS Chem Biol. 2014 Sep 19;9(9):1980-4

  59. Teufel R, Kaysser L, Villaume MT, Diethelm S, Carbullido MK, Baran PS, Moore BS
    One-Pot Enzymatic Synthesis of Merochlorin A and B.
    Angew Chem Int Ed Engl. 2014 Oct 6;53(41):11019-22

  60. Diethelm S, Teufel R, Kaysser L, Moore BS
    A Multitasking Vanadium-Dependent Chloroperoxidase as an Inspiration for the Chemical Synthesis of the Merochlorins.
    Angew Chem Int Ed Engl. 2014 Oct 6;53(41):11023-6

  61. Moree WJ, McConnell OJ, Nguyen DD, Sanchez LM, Yang YL, Zhao X, Liu WT, Boudreau PD, Srinivasan J, Atencio L, Ballesteros J, Gavilán RG, Torres-Mendoza D, Guzmán HM, Gerwick WH, Gutiérrez M, Dorrestein PC
    Microbiota of healthy corals are active against fungi in a light-dependent manner.
    ACS Chem Biol. 2014 Oct 17;9(10):2300-8

  62. Mevers E, Matainaho T, Allara' M, Di Marzo V, Gerwick WH
    Mooreamide A: A Cannabinomimetic Lipid from the Marine Cyanobacterium Moorea bouillonii.
    Lipids. 2014 Nov;49(11):1127-32

  63. Jamison MT, Boddy CN, Molinski TF
    Salvadenosine, a 5'-Deoxy-5'-(methylthio) Nucleoside from the Bahamian Tunicate Didemnum sp.
    J Org Chem. 2014 Nov 7;79(21):9992-9997

  64. Mehrotra S, Duggan BM, Tello-Aburto R, Newar TD, Gerwick WH, Murray TF, Maio WA
    Detailed analysis of (-)-palmyrolide a and some synthetic derivatives as voltage-gated sodium channel antagonists.
    J Nat Prod. 2014 Nov 26;77(11):2553-60

    65. 2015

  65. Lux J, White AG, Chan M, Anderson CJ, Almutairi A
    Nanogels from Metal-Chelating Crosslinkers as Versatile Platforms Applied to Copper-64 PET Imaging of Tumors and Metastases.
    Theranostics. 2015 Jan 1;5(3):277-88

  66. Carling CJ, Viger ML, Huu VA, Garcia AV, Almutairi A
    In vivo vivsible light-triggered drug release from an implanted depot
    Chem. Sci. 2015 Jan 1;6(1):335-341

  67. Agarwal V, Li J, Rahman I, Borgen M, Aluwihare LI, Biggs JS, Paul VJ, Moore BS
    Complexity of naturally produced polybrominated diphenyl ethers revealed via mass spectrometry.
    Environ Sci Technol. 2015 Feb 3;49(3):1339-46

  68. Huu VA, Luo J, Zhu J, Zhu J, Patel S, Boone A, Mahmoud E, McFearin C, Olejniczak J, de Gracia Lux C, Lux J, Fomina N, Huynh M, Zhang K, Almutairi A.
    Light-responsive nanoparticle depot to control release of a small molecule angiogenesis inhibitor in the posterior segment of the eye.
    J Control Release. 2015 Feb 28;200:71-7

  69. Bonet B, Teufel R, Crüsemann M, Ziemert N, Moore BS
    Direct capture and heterologous expression of Salinispora natural product genes for the biosynthesis of enterocin.
    J Nat Prod. 2015 Mar 27;78(3):539-42

  70. Jamison MT, Molinski TF
    Antipodal Crambescin A2 Homologues from the Marine Sponge Pseudaxinella reticulata. Antifungal Structure-Activity Relationships.
    J Nat Prod. 2015 Mar 27;78(3):557-61

  71. Duncan KR, Crüsemann M, Lechner A, Sarkar A, Li J, Ziemert N, Wang M, Bandeira N, Moore BS, Dorrestein PC, Jensen PR
    Molecular Networking and Pattern-Based Genome Mining Improves Discovery of Biosynthetic Gene Clusters and their Products from Salinispora Species.
    Chem Biol. 2015 Apr 23;22(4):460-71

  72. Grover GN, Garcia J, Nguyen MM, Zanotelli M, Madani MM, Christman KL
    Binding of Anticell Adhesive Oxime-Crosslinked PEG Hydrogels to Cardiac Tissues.
    Adv Healthc Mater. 2015 Jun 24;4(9):1327-31

  73. Richter TK, Hughes CC, Moore BS
    Sioxanthin, a novel glycosylated carotenoid reveals an unusual subclustered biosynthetic pathway.
    Environ Microbiol. 2015 Jun;17(6):2158-71

  74. Awakawa T, Crüsemann M, Munguia J, Ziemert N, Nizet V, Fenical W, Moore BS
    Salinipyrone and pacificanone are biosynthetic byproducts of the rosamicin polyketide synthase.
    Chembiochem. 2015 Jul 6;16(10):1443-7

  75. Kleigrewe K, Almaliti J, Tian IY, Kinnel RB, Korobeynikov A, Monroe EA, Duggan BM, Di Marzo V, Sherman DH, Dorrestein PC, Gerwick L, Gerwick WH
    Combining Mass Spectrometric Metabolic Profiling with Genomic Analysis: A Powerful Approach for Discovering Natural Products from Cyanobacteria.
    J Nat Prod. 2015 Jul 24;78(7):1671-82

  76. Boudreau PD, Monroe EA, Mehrotra S, Desfor S, Korobeynikov A, Sherman DH, Murray TF, Gerwick L, Dorrestein PC, Gerwick WH
    Expanding the Described Metabolome of the Marine Cyanobacterium Moorea producens JHB through Orthogonal Natural Products Workflows.
    PLOS One. 2015 Jul 29;10(7):e0133297

  77. Leão PN, Nakamura H, Costa M, Pereira AR, Martins R, Vasconcelos V, Gerwick WH, Balskus EP
    Biosynthesis-Assisted Structural Elucidation of the Bartolosides, Chlorinated Aromatic Glycolipids from Cyanobacteria.
    Angew Chem Int Ed Engl. 2015 Jul 31;54(38):11063-7

  78. Álvarez-Micó X, Rocha DD, Guimarães LA, Ambrose A, Chapman E, Costa-Lotufo LV, La Clair JJ, Fenical W
    The Hybrid Pyrroloisoindolone-Dehydropyrrolizine Alkaloid (-)-Chlorizidine A Targets Proteins within the Glycolytic Pathway.
    Chembiochem. 2015 Aug 12;16(14):2002-6

  79. Wang X, Duggan BM, Molinski TF
    Mollenynes B-E from the Marine Sponge Spirastrella mollis. Band-Selective HSQC for Discrimination of Bromo-chloro Regioisomerism in Natural Products.
    J Am Chem Soc. 2015 Sep 3;137(38):12343-51

  80. Olejniczak J, Nguyen Huu VA, Lux J, Grossman M, He S, Almutairi A
    Light-triggered chemical amplification to accelerate degradation and release from polymeric particles.
    Chem Commun. 2015 Nov 17;51(95):16980-3

  81. Tang X, Li J, Millán-Aguiñaga N, Zhang JJ, O'Neill EC, Ugalde JA, Jensen PR, Mantovani SM, Moore BS
    Identification of Thiotetronic Acid Antibiotic Biosynthetic Pathways by Target-directed Genome Mining.
    ACS Chem Biol. 2015 Dec 18;10(12):2841-9

    82. 2016

  82. Ray L, Yamanaka K, Moore BS
    A Peptidyl-Transesterifying Type I Thioesterase in Salinamide Biosynthesis.
    Angew Chem Int Ed Engl. 2016 Jan 4;55(1):364-7

  83. Bertin MJ, Vulpanovici A, Monroe EA, Korobeynikov A, Sherman DH, Gerwick L, Gerwick WH
    The Phormidolide Biosynthetic Gene Cluster: A trans-AT PKS Pathway Encoding a Toxic Macrocyclic Polyketide.
    Chembiochem. 2016 Jan;17(2):164-73

  84. Bertin MJ, Demirkiran O, Navarro G, Moss NA, Lee J, Goldgof GM, Vigil E, Winzeler EA, Valeriote FA, Gerwick WH
    Kalkipyrone B, a marine cyanobacterial γ-pyrone possessing cytotoxic and anti-fungal activities.
    Phytochemistry. 2016 Feb;122:113-8

  85. White AR, Duggan BM, Tsai SC, Vanderwal CD
    The Alga Ochromonas danica Produces Bromosulfolipids.
    Org Lett. 2016 Feb 18;18(5):1124-7

  86. Carling CJ, Olejniczak J, Foucault-Collet A, Collet G, Viger ML, Huu VA, Duggan BM, Almutairi A
    Efficient Red Light Photo-Uncaging of Active Molecules in Water Upon Assembly into Nanoparticles.
    Chem Sci. 2016 Mar;7(3):2392-2398

  87. Zhang ZN, Freitas BC, Qian H, Lux J, Acab A, Trujillo CA, Herai RH, Nguyen Huu VA, Wen JH, Joshi-Barr S, Karpiak JV, Engler AJ, Fu XD, Muotri AR, Almutairi A
    Layered hydrogels accelerate iPSC-derived neuronal maturation and reveal migration defects caused by MeCP2 dysfunction.
    Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3185-90

  88. Jamison MT, Dalisay DS, Molinski TF
    Peroxide Natural Products from Plakortis zyggompha and the Sponge Association Plakortis halichondrioides-Xestospongia deweerdtae: Antifungal Activity against Cryptococcus gattii.
    J Nat Prod. 2016 Mar 25;79(3):555-63

  89. El Gamal A, Agarwal V, Diethelm S, Rahman I, Schorn MA, Sneed JM, Louie GV, Whalen KE, Mincer TJ, Noel JP, Paul VJ, Moore BS
    Biosynthesis of coral settlement cue tetrabromopyrrole in marine bacteria by a uniquely adapted brominase-thioesterase enzyme pair.
    Proc Natl Acad Sci U S A. 2016 Apr 5;113(14):3797-802

  90. Johnson TC, Chin MR, Han T, Shen JP, Rana T, Siegel D
    Synthesis of Eupalinilide E, a Promoter of Human Hematopoietic Stem and Progenitor Cell Expansion.
    J Am Chem Soc. 2016 May 11;138(18):6068-73

  91. Wang M, Carver JJ, Phelan VV, Sanchez LM, Garg N, Peng Y, Nguyen DD, Watrous J, Kapono CA, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik AV, Meehan MJ, Liu WT, Crüsemann M, Boudreau PD, Esquenazi E, Sandoval-Calderón M, Kersten RD, Pace LA, Quinn RA, Duncan KR, Hsu CC, Floros DJ, Gavilan RG, Kleigrewe K, Northen T, Dutton RJ, Parrot D, Carlson EE, Aigle B, Michelsen CF, Jelsbak L, Sohlenkamp C, Pevzner P, Edlund A, McLean J, Piel J, Murphy BT, Gerwick L, Liaw CC, Yang YL, Humpf HU, Maansson M, Keyzers RA, Sims AC, Johnson AR, Sidebottom AM, Sedio BE, Klitgaard A, Larson CB, Boya P CA, Torres-Mendoza D, Gonzalez DJ, Silva DB, Marques LM, Demarque DP, Pociute E, O'Neill EC, Briand E, Helfrich EJ, Granatosky EA, Glukhov E, Ryffel F, Houson H, Mohimani H, Kharbush JJ, Zeng Y, Vorholt JA, Kurita KL, Charusanti P, McPhail KL, Nielsen KF, Vuong L, Elfeki M, Traxler MF, Engene N, Koyama N, Vining OB, Baric R, Silva RR, Mascuch SJ, Tomasi S, Jenkins S, Macherla V, Hoffman T, Agarwal V, Williams PG, Dai J, Neupane R, Gurr J, Rodríguez AM, Lamsa A, Zhang C, Dorrestein K, Duggan BM, Almaliti J, Allard PM, Phapale P, Nothias LF, Alexandrov T, Litaudon M, Wolfender JL, Kyle JE, Metz TO, Peryea T, Nguyen DT, VanLeer D, Shinn P, Jadhav A, Müller R, Waters KM, Shi W, Liu X, Zhang L, Knight R, Jensen PR, Palsson BØ, Pogliano K, Linington RG, Gutiérrez M, Lopes NP, Gerwick WH, Moore BS, Dorrestein PC, Bandeira N
    Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking.
    Nat Biotechnol. 2016 Aug 9;34(8):828-837

  92. Jamison MT, Molinski TF
    Jamaicensamide A, a Peptide Containing β-Amino-α-keto and Thiazole-Homologated η-Amino Acid Residues from the Sponge Plakina jamaicensis.
    J Nat Prod. 2016 Sep 23;79(9):2243-9

  93. Li ZR, Li J, Gu JP, Lai JY, Duggan BM, Zhang WP, Li ZL, Li YX, Tong RB, Xu Y, Lin DH, Moore BS, Qian PY
    Divergent biosynthesis yields a cytotoxic aminomalonate-containing precolibactin.
    Nat Chem Biol. 2016 Oct;12(10):773-5

  94. Nguyen DD, Melnik AV, Koyama N, Lu X, Schorn M, Fang J, Aguinaldo K, Lincecum TL Jr, Ghequire MG, Carrion VJ, Cheng TL, Duggan BM, Malone JG, Mauchline TH, Sanchez LM, Kilpatrick AM, Raaijmakers JM, Mot R, Moore BS, Medema MH, Dorrestein PC
    Indexing the Pseudomonas specialized metabolome enabled the discovery of poaeamide B and the bananamides.
    Nat Microbiol. 2016 Oct 31;2:16197

  95. Jordan PA, Moore BS
    Biosynthetic Pathway Connects Cryptic Ribosomally Synthesized Posttranslationally Modified Peptide Genes with Pyrroloquinoline Alkaloids.
    Cell Chem Biol. 2016 Nov 9. pii: S2451-9456(16)30387-7

  96. Gingras AR, Puzon-McLaughlin W, Bobkov AA, Ginsberg MH
    Structural Basis of Dimeric Rasip1 RA Domain Recognition of the Ras Subfamily of GTP-Binding Proteins.
    Structure. 2016 Dec 6;24(12):2152-2162

    97. 2017

  97. Handley LD, Fuglestad B, Stearns K, Tonelli M, Fenwick RB, Markwick PR, Komives EA
    NMR reveals a dynamic allosteric pathway in thrombin.
    Sci Rep. 2017 Jan 6;7:39575

  98. Olejniczak J, Collet G, Nguyen Huu VA, Chan M, Lee S, Almutairi A
    Biorthogonal click chemistry on poly(lactic-co-glycolic acid)-polymeric particles.
    Biomater Sci. 2017 Jan 31;5(2):211-215

  99. Kantonen SA, Henriksen NM, Gilson MK
    Evaluation and Minimization of Uncertainty in ITC Binding Measurements: Heat Error, Concentration Error, Saturation, and Stoichiometry.
    Biochim Biophys Acta. 2017 Feb;1861(2):485-498

  100. Kaczanowska K, Camacho Hernandez GA, Bendiks L, Kohs L, Cornejo-Bravo JM, Harel M, Finn MG, Taylor P
    Substituted 2-Aminopyrimidines Selective for α7-Nicotinic Acetylcholine Receptor Activation and Association with Acetylcholine Binding Proteins.
    J Am Chem Soc. 2017 Mar 15;139(10):3676-3684

  101. Viger ML, Collet G, Lux J, Nguyen Huu VA, Guma M, Foucault-Collet A, Olejniczak J, Joshi-Barr S, Firestein GS, Almutairi A
    Distinct ON/OFF fluorescence signals from dual-responsive activatable nanoprobes allows detection of inflammation with improved contrast.
    Biomaterials. 2017 Mar 28;133:119-131

  102. Wang X, Duggan BM, Molinski TF
    Ultra-high resolution band-selective HSQC for nanomole-scale identification of chlorine-substituted 13C in natural products drug discovery.
    Magn Reson Chem. 2017 Apr;55(4):263-268

  103. Nelson AT, Kolar MJ, Chu Q, Syed I, Kahn BB, Saghatelian A, Siegel D
    Stereochemistry of Endogenous Palmitic Acid Ester of 9-Hydroxystearic Acid and Relevance of Absolute Configuration to Regulation.
    J Am Chem Soc. 2017 Apr 5;139(13):4943-4947

  104. Zhang C, Naman CB, Engene N, Gerwick WH
    Laucysteinamide A, a Hybrid PKS/NRPS Metabolite from a Saipan Cyanobacterium, cf. Caldora penicillata.
    Mar Drugs. 2017 Apr 14;15(4). pii: E121

  105. Larson CB, Crüsemann M, Moore BS
    PCR-Independent Method of Transformation-Associated Recombination Reveals the Cosmomycin Biosynthetic Gene Cluster in an Ocean Streptomycete.
    J Nat Prod. 2017 Apr 28;80(4):1200-1204

  106. Agarwal V, Blanton JM, Podell S, Taton A, Schorn MA, Busch J, Lin Z, Schmidt EW, Jensen PR, Paul VJ, Biggs JS, Golden JW, Allen EE, Moore BS
    Metagenomic discovery of polybrominated diphenyl ether biosynthesis by marine sponges.
    Nat Chem Biol. 2017 May;13(5):537-543

  107. Johnson TC, Chin MR, Siegel D
    Synthetic Route Development for the Laboratory Preparation of Eupalinilide E.
    J Org Chem. 2017 May 5;82(9):4640-4653

  108. Luzzatto Knaan T, Garg N, Wang M, Glukhov E, Peng Y, Ackermann G, Amir A, Duggan BM, Ryazanov S, Gerwick L, Knight R, Alexandrov T, Bandeira N, Gerwick WH, Dorrestein PC
    Digitizing mass spectrometry data to explore the chemical diversity and distribution of marine cyanobacteria and algae.
    Elife. 2017 May 11;6. pii: e24214

  109. Tang X, Li J, Moore BS
    Minimization of the Thiolactomycin Biosynthetic Pathway Reveals that the Cytochrome P450 Enzyme TlmF is Required for Five-membered Thiolactone Ring Formation.
    Chembiochem. 2017 Jun 19;18(12):1072-1076

  110. Fang X, Bogomolovas J, Wu T, Zhang W, Liu C, Veevers J, Stroud MJ, Zhang Z, Ma X, Mu Y, Lao DH, Dalton ND, Gu Y, Wang C, Wang M, Liang Y, Lange S, Ouyang K, Peterson KL, Evans SM, Chen J
    Loss-of-function mutations in co-chaperone BAG3 destabilize small HSPs and cause cardiomyopathy.
    J Clin Invest. 2017 Aug 1;127(8):3189-3200

  111. Naman CB, Almaliti J, Armstrong L, Caro-Díaz EJ, Pierce ML, Glukhov E, Fenner A, Spadafora C, Debonsi HM, Dorrestein PC, Murray TF, Gerwick WH
    Discovery and Synthesis of Caracolamide A, an Ion Channel Modulating Dichlorovinylidene Containing Phenethylamide from a Panamanian Marine Cyanobacterium cf. Symploca Species.
    J Nat Prod. 2017 Aug 25;80(8):2328-2334

  112. Li J, Tang X, Awakawa T, Moore BS
    Enzymatic C-H Amidation in the Production of Natural and Unnatural Thiotetronate Antibiotics with Potentiated Bioactivity.
    Angew Chem Int Ed Engl. 2017 Sep 25;56(40):12234-12239

  113. Zhang C, Idelbayev Y, Roberts N, Tao Y, Nannapaneni Y, Duggan BM, Min J, Lin EC, Gerwick EC, Cottrell GW, Gerwick WH
    Small Molecule Accurate Recognition Technology (SMART) to Enhance Natural Products Research.
    Sci Rep. 2017 Oct 27;7(1):14243

  114. Lee S, Stubelius A, Olejniczak J, Jang H, Huu VAN, Almutairi A
    Chemical amplification accelerates reactive oxygen species triggered polymeric degradation.
    Biomater Sci. 2017 Dec 19;6(1):107-114

  115. Miles ZD, Diethelm S, Pepper HP, Huang DM, George JH, Moore BS
    A unifying paradigm for naphthoquinone-based meroterpenoid (bio)synthesis.
    Nat Chem. 2017 Dec;9(12):1235-1242

    116. 2018

  116. Bruns H, Crüsemann M, Letzel AC, Alanjary M, McInerney JO, Jensen PR, Schulz S, Moore BS, Ziemert N
    Function-related replacement of bacterial siderophore pathways.
    ISME J. 2018 Feb;12(2):320-329

  117. Reynolds KA, Luhavaya H, Li J, Dahesh S, Nizet V, Yamanaka K, Moore BS
    Isolation and structure elucidation of lipopeptide antibiotic taromycin B from the activated taromycin biosynthetic gene cluster.
    J Antibiot (Tokyo). 2018 Feb;71(2):333-338

  118. Salib MN, Molinski TF
    Six Trikentrin-like Cyclopentanoindoles from Trikentrion flabelliforme. Absolute Structural Assignment by NMR and ECD.
    J Org Chem. 2018 Feb 2;83(3):1278-1286

  119. Syed I, Lee J, Moraes-Vieira PM, Donaldson CJ, Sontheimer A, Aryal P, Wellenstein K, Kolar MJ, Nelson AT, Siegel D, Mokrosinski J, Farooqi IS, Zhao JJ, Yore MM, Peroni OD, Saghatelian A, Kahn BB
    Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis.
    Cell Metab. 2018 Feb 6;27(2):419-427.e4

  120. Kantonen SA, Henriksen NM, Gilson MK
    Accounting for apparent deviations between calorimetric and van't Hoff enthalpies.
    Biochim Biophys Acta. 2018 Mar;1862(3):692-704

  121. Debnath A, Nelson AT, Silva-Olivares A, Shibayama M, Siegel D, McKerrow JH
    In Vitro Efficacy of Ebselen and BAY 11-7082 Against Naegleria fowleri.
    Front Microbiol. 2018 Mar 6;9:414

  122. Tao Y, Li P, Zhang D, Glukhov E, Gerwick L, Zhang C, Murray TF, Gerwick WH
    Samholides, Swinholide-Related Metabolites from a Marine Cyanobacterium cf. Phormidium sp.
    J Org Chem. 2018 Mar 16;83(6):3034-3046

  123. Gartshore CJ, Salib MN, Renshaw AA, Molinski TF
    Isolation of bastadin-6-O-sulfate and expedient purifications of bastadins-4, -5 and -6 from extracts of Ianthella basta.
    Fitoterapia. 2018 Apr;126:16-21

  124. Kolar MJ, Nelson AT, Chang T, Ertunc ME, Christy MP, Ohlsson L, Härröd M, Kahn BB, Siegel D, Saghatelian A
    Faster Protocol for Endogenous Fatty Acid Esters of Hydroxy Fatty Acid (FAHFA) Measurements.
    Anal Chem. 2018 Apr 17;90(8):5358-5365

  125. O'Rourke A, Kremb S, Duggan BM, Sioud S, Kharbatia N, Raji M, Emwas AH, Gerwick WH, Voolstra CR
    Identification of a 3-Alkylpyridinium Compound from the Red Sea Sponge Amphimedon chloros with In Vitro Inhibitory Activity against the West Nile Virus NS3 Protease.
    Molecules. 2018 Jun 18;23(6), 1472

  126. Oukoloff K, Kovalevich J, Cornec AS, Yao Y, Owyang ZA, James M, Trojanowski JQ, Lee VM, Smith AB 3rd, Brunden KR, Ballatore C
    Design, synthesis and evaluation of photoactivatable derivatives of microtubule (MT)-active [1,2,4]triazolo[1,5-a]pyrimidines.
    Bioorg Med Chem Lett. 2018 Jul 1;28(12):2180-2183

  127. Stubelius A, Sheng W, Lee S, Olejniczak J, Guma M, Almutairi A
    Disease-Triggered Drug Release Effectively Prevents Acute Inflammatory Flare-Ups, Achieving Reduced Dosing.
    Small. 2018 Jul 15:e1800703

  128. Monti L, Wang SC, Oukoloff K, Smith AB, Brunden KR, Caffrey C, Ballatore C
    Brain-penetrant, triazolopyrimidine and phenylpyrimidine microtubule-stabilizers as potential leads to treat human African trypanosomiasis.
    ChemMedChem. 2018 Sep 6;13(17):1751-1754

  129. Lagarrigue F, Gingras AR, Paul DS, Valadez AJ, Cuevas MN, Sun H, Lopez-Ramirez MA, Goult BT, Shattil SJ, Bergmeier W, Ginsberg MH
    Rap1 binding to the talin 1 F0 domain makes a minimal contribution to murine platelet GPIIb-IIIa activation.
    Blood Adv. 2018 Sep 25;2(18):2358-2368

  130. Brunson JK, McKinnie SMK, Chekan JR, McCrow JP, Miles ZD, Bertrand EM, Bielinski VA, Luhavaya H, Oborník M, Smith GJ, Hutchins DA, Allen AE, Moore BS
    Biosynthesis of the neurotoxin domoic acid in a bloom-forming diatom.
    Science. 2018 Sep 28;361(6409):1356-1358

  131. Kellett K, Kantonen SA, Duggan, BM, Gilson MK
    Toward Expanded Diversity of Host–Guest Interactions via Synthesis and Characterization of Cyclodextrin Derivatives
    J Solution Chem. 2018 Nov;47:1597-1608

  132. Sit RK, Kovarik Z, Maček Hrvat N, Žunec S, Green C, Fokin VV, Sharpless KB, Radić Z and Taylor P
    Pharmacology, Pharmacokinetics, and Tissue Disposition of Zwitterionic Hydroxyiminoacetamido Alkylamines as Reactivating Antidotes for Organophosphate Exposure
    J Pharmacol Exp Ther. 2018 Nov;367(2):363-372

  133. Zhang B, Yao Y, Cornec AS, Oukoloff K, James MJ, Koivula P, Trojanowski JQ, Smith AB 3rd, Lee VM, Ballatore C, Brunden KR
    A brain-penetrant triazolopyrimidine enhances microtubule-stability, reduces axonal dysfunction and decreases tau pathology in a mouse tauopathy model.
    Mol Neurodegener. 2018 Nov 7;13(1):59

  134. Ómarsdóttir S, Wang X, Liu HB, Duggan BM, Molinski TF
    Lepadins I-K, 3- O-(3'-Methylthio)acryloyloxy-decahydroquinoline Esters from a Bahamian Ascidian Didemnum sp. Assignment of Absolute Stereostructures.
    J Org Chem. 2018 Nov 16;83(22):13670-13677

  135. McKinnie SMK, Miles ZD, Jordan PA, Awakawa T, Pepper HP, Murray LAM, George JH, Moore BS
    Total Enzyme Syntheses of Napyradiomycins A1 and B1.
    J Am Chem Soc. 2018 Dec 26;140(51):17840-17845

    136. 2019

  136. Pearce AN, Copp BR, Molinski TF
    Enantiomeric Variability of Distaminolyne A. Refinement of ECD and NMR Methods for Determining Optical Purity of 1-Amino-2-Alkanols.
    Molecules. 2019 Jan;24(1):90

  137. Kellett K, Duggan BM, Gilson MK
    Facile Synthesis of a Diverse Library of Mono-3-substituted β-Cyclodextrin Analogues
    Supramolecular Chemistry. 2019 Jan 6;31(4):251-259

  138. Jamison MT, Wang X, Cheng T, Molinski TF
    Synergistic Anti-Candida Activity of Bengazole A in the Presence of Bengamide A
    Mar Drugs. 2019 Feb 7;17(2):102

  139. Kovarik Z, Kalisiak J, Hrvat NM, Katalinić M, Zorbaz T, Žunec S, Green C, Radić Z, Fokin VV, Sharpless KB, Taylor P
    Reversal of tabun toxicity, enabled by a triazole annulated oxime library-reactivators of acetylcholinesterase.
    Chemistry. 2019 Mar 15;25(16):4100-4114

  140. Shang Z, Winter JM, Kauffman CA, Yang I, Fenical W
    Salinipeptins: Integrated Genomic and Chemical Approaches Reveal Unusual d-Amino Acid-Containing Ribosomally Synthesized and Post-Translationally Modified Peptides (RiPPs) from a Great Salt Lake Streptomyces sp.
    ACS Chem Biol. 2019 Mar 15;14(3):415-425

  141. Rothe ML, Li J, Garibay E, Moore BS, McKinnie SMK
    Synthesis, bioactivity, and enzymatic modification of antibacterial thiotetromycin derivatives.
    Org Biomol Chem. 2019 Mar 27;17(13):3416-3423

  142. Bauman KD, Li J, Murata K, Mantovani SM, Dahesh S, Nizet V, Luhavaya H, Moore BS
    Refactoring the Cryptic Streptophenazine Biosynthetic Gene Cluster Unites Phenazine, Polyketide, and Nonribosomal Peptide Biochemistry.
    Cell Chem Biol. 2019 May 16;26(5):724-736.e7

  143. Wang H, Chang T, Konduri S, Huang J, Saghatelian A, Siegel D
    Synthesis of chemically edited derivatives of the endogenous regulator of inflammation 9-PAHSA.
    J Antibiot (Tokyo). 2019 Jun;72(6):498-506

  144. Gingras AR, Lagarrigue F, Cuevas MN, Valadez AJ, Zorovich M, McLaughlin W, Lopez-Ramirez MA, Seban N, Ley K, Kiosses WB, Ginsberg MH
    Rap1 binding and a lipid-dependent helix in talin F1 domain promote integrin activation in tandem.
    J Cell Biol. 2019 Jun. 218(6):1799-1809

  145. Luhavaya H, Sigrist R, Chekan JR, McKinnie SMK, Moore BS
    Biosynthesis of L-4-Chlorokynurenine, an Antidepressant Prodrug and a Non-Proteinogenic Amino Acid Found in Lipopeptide Antibiotics
    Angew Chem Int Ed Engl. 2019 Jun 17;58(25):8394-8399

  146. Chekan JR, McKinnie SMK, Moore ML, Poplawski SG, Michael TP, Moore BS
    Scalable biosynthesis of the seaweed neurochemical kainic acid.
    Angew Chem Int Ed Engl. 2019 Jun 17;58(25):8454-8457

  147. Moss NA, Seiler G, Leão TF, Castro-Falcón G, Gerwick L, Hughes CC, Gerwick WH
    Nature's combinatorial biosynthesis produces vatiamides A-F.
    Angew Chem Int Ed Engl. 2019 Jul 1;58(27):9027-9031

  148. Syed I, Rubin de Celis MF, Mohan JF, Moraes-Vieira PM, Vijayakumar A, Nelson AT, Siegel D, Saghatelian A, Mathis D, Kahn BB
    PAHSAs attenuate immune responses and promote β cell survival in autoimmune diabetic mice.
    J Clin Invest. 2019 Aug 5;129(9):3717-3731

  149. Yu HB, Glukhov E, Li Y, Iwasaki A, Gerwick L, Dorrestein PC, Jiao BH, Gerwick WH
    Cytotoxic Microcolin Lipopeptides from the Marine Cyanobacterium Moorea producens.
    J Nat Prod. 2019 Sep 27;82(9):2608-2619

  150. Zhou P, Santoro A, Peroni OD, Nelson AT, Saghatelian A, Siegel D, Kahn BB
    PAHSAs enhance hepatic and systemic insulin sensitivity through direct and indirect mechanisms.
    J Clin Invest. 2019 Oct 1;129(10):4138-4150

  151. Meewan I, Zhang X, Roy S, Ballatore C, O'Donoghue AJ, Schooley RT, Abagyan R
    Discovery of New Inhibitors of Hepatitis C Virus NS3/4A Protease and Its D168A Mutant.
    ACS Omega. 2019 Oct 2;4(16):16999-17008

  152. Wang H, Kolar MJ, Chang T, Rizo J, Konduri S, McNerlin C, Saghatelian A, Siegel D
    Stereochemistry of Linoleic Acid Esters of Hydroxy Linoleic Acids.
    Org Lett. 2019 Oct 4;21(19):8080-8084

  153. Schubert D, Kepchia D, Liang Z, Dargusch R, Goldberg J, Maher P
    Efficacy of Cannabinoids in a Pre-Clinical Drug-Screening Platform for Alzheimer's Disease.
    Mol Neurobiol. 2019 Nov;56(11):7719-7730

  154. Camacho-Hernandez GA, Stokes C, Duggan BM, Kaczanowska K, Brandao-Araiza S, Doan L, Papke RL, Taylor P
    Synthesis, pharmacological characterization, and structure-activity relationships of non-canonical selective agonists for α7 nAChRs.
    J Med Chem. 2019 Nov 27;62(22):10376-10390

    155. 2020

  155. Duggan BM, Cullum R, Fenical W, Amador LA, Rodríguez AD, La Clair JJ
    Searching for Small Molecules with an Atomic Sort.
    Angew Chem Int Ed Engl. 2020 Jan 13;59(3):1144-1148.

  156. Danielsson J, Noel JK, Simien JM, Duggan BM, Oliveberg M, Onuchic JN, Jennings PA, Haglund E
    The pierced lasso topology leptin has a bolt on dynamic domain composed by the disordered loops I and III.
    J Mol Biol. 2020 Feb 17. pii: S0022-2836(20)30101-7

  157. Reher R, Kim HW, Zhang C, Mao HH, Wang M, Nothias LF, Caraballo-Rodriguez AM, Glukhov E, Teke B, Leao T, Alexander KL, Duggan BM, Van Everbroeck EL, Dorrestein PC, Cottrell GW, Gerwick WH
    A Convolutional Neural Network-Based Approach for the Rapid Annotation of Molecularly Diverse Natural Products.
    J Am Chem Soc. 2020 Mar 4;142(9):4114-4120

  158. Keller L, Canuto KM, Liu C, Suzuki BM, Almaliti J, Sikandar A, Naman CB, Glukhov E, Luo D, Duggan BM, Luesch H, Koehnke J, O'Donoghue AJ, Gerwick WH
    Tutuilamides A-C: Vinyl-Chloride-Containing Cyclodepsipeptides from Marine Cyanobacteria with Potent Elastase Inhibitory Properties.
    ACS Chem Biol. 2020 Mar 20;15(3):751-757

  159. Christy MP, Johnson T, McNerlin CD, Woodard J, Nelson AT, Lim B, Hamilton TL, Freiberg KM, Siegel D
    Total Synthesis of Micrococcin P1 through Scalable Thiazole Forming Reactions of Cysteine Derivatives and Nitriles.
    Org Lett. 2020 Mar 20;22(6):2365-2370

  160. Gorecki L, Gerlits O, Kong X, Cheng X, Blumenthal DK, Taylor P, Ballatore C, Kovalevsky A, Radić Z
    Rational design, synthesis, and evaluation of uncharged, "smart" bis-oxime antidotes of organophosphate-inhibited human acetylcholinesterase.
    J Biol Chem. 2020 Mar 27;295(13):4079-4092

  161. Keller L, Siqueira-Neto JL, Souza JM, Eribez K, LaMonte GM, Smith JE, Gerwick WH
    Palstimolide A: A Complex Polyhydroxy Macrolide with Antiparasitic Activity.
    Molecules. 2020 Mar 31;25(7):1604

  162. Tang X, Kudo Y, Baker JL, LaBonte S, Jordan PA, McKinnie SMK, Guo J, Huan T, Moore BS, Edlund A
    Cariogenic Streptococcus mutans Produces Tetramic Acid Strain-Specific Antibiotics That Impair Commensal Colonization.
    ACS Infect Dis. 2020 Apr 10;6(4):563-571

  163. LaMonte GM, Rocamora F, Marapana DS, Gnädig NF, Ottilie S, Luth MR, Worgall TS, Goldgof GM, Mohunlal R, Santha Kumar TR, Thompson JK, Vigil E, Yang J, Hutson D, Johnson T, Huang J, Williams RM, Zou BY, Cheung AL, Kumar P, Egan TJ, Lee MCS, Siegel D, Cowman AF, Fidock DA, Winzeler EA
    Pan-active imidazolopiperazine antimalarials target the Plasmodium falciparum intracellular secretory pathway.
    Nat Commun. 2020 Apr 14;11(1):1780

  164. Wirth DM, Jaquez A, Gandarilla S, Hochberg JD, Church DC, Pokorski JK
    Highly Expandable Foam for Lithographic 3D Printing.
    ACS Appl Mater Interfaces. 2020 Apr 22;12(16):19033-19043

  165. Uranga CC, Arroyo P Jr, Duggan BM, Gerwick WH, Edlund A
    Commensal Oral Rothia mucilaginosa Produces Enterobactin, a Metal-Chelating Siderophore.
    mSystems. 2020 Apr 28;5(2). pii: e00161-20

  166. Hsu PH, Arboleda C, Stubelius A, Li LW, Olejniczak J, Almutairi A
    Highly responsive and rapid hydrogen peroxide-triggered degradation of polycaprolactone nanoparticles.
    Biomater Sci. 2020 May 6;8(9):2394-2397

  167. Salib MN, Jamison MT, Molinski TF
    Bromo-spiroisoxazoline Alkaloids, Including an Isoserine Peptide, from the Caribbean Marine Sponge Aplysina lacunosa.
    J Nat Prod. 2020 May 22;83(5):1532-1540

  168. Skepper CK, Molinski TF
    Synchronous bond molecular dynamics of conjugated chlorocyclopropyl alk-yn-enes revealed by ECD and UV-vis.
    Chirality. 2020 Jun 21;32:1037-1044

  169. Church DC, Pokorski JK
    Cell Engineering with Functional Poly(oxanorbornene) Block Copolymers.
    Angew Chem Int Ed Engl. 2020 Jul 6;59(28):11379-11383

  170. Church DC, Takiguchi L, Pokorski JK
    Optimization of Ring-Opening Metathesis Polymerization (ROMP) under Physiologically Relevant Conditions.
    Polym Chem. 2020 Jul 21;11(27):4492-4499

  171. Zhang J, Huang X, Guo B, Cooper S, Capitano ML, Johnson TC, Siegel DR, Broxmeyer HE
    Effects of Eupalinilide E and UM171, alone and in combination on cytokine stimulated ex-vivo expansion of human cord blood hematopoietic stem cells.
    Blood Cells Mol Dis. 2020 Sep;84:102457

  172. Leber CA, Naman CB, Keller L, Almaliti J, Caro-Diaz EJE, Glukhov E, Joseph V, Sajeevan TP, Reyes AJ, Biggs JS, Li T, Yuan Y, He S, Yan X, Gerwick WH
    Applying a Chemogeographic Strategy for Natural Product Discovery from the Marine Cyanobacterium Moorena bouillonii.
    Mar Drugs. 2020 Oct 14;18(10):515

  173. Konduri S, Prashanth J, Krishna VS, Sriram D, Behera JN, Siegel D, Rao KP
    Design and Synthesis of Purine Connected Piperazine Derivatives as Novel Inhibitors of Mycobacterium tuberculosis.
    Bioorg Med Chem Lett. 2020 Nov 15;30(22):127512

  174. Kudo Y, Awakawa T, Du YL, Jordan PA, Creamer KE, Jensen PR, Linington RG, Ryan KS, Moore BS
    Expansion of Gamma-Butyrolactone Signaling Molecule Biosynthesis to Phosphotriester Natural Products.
    ACS Chem Biol. 2020 Dec 18;15(12):3253-3261

    175. 2021

  175. Kellett K, Slochower DR, Schauperl M, Duggan BM, Gilson MK
    Experimental characterization of the association of β-cyclodextrin and eight novel cyclodextrin derivatives with two guest compounds.
    J Comput Aided Mol Des. 2021 Jan;35(1):95-104

  176. Oukoloff K, Nzou G, Varricchio C, Lucero B, Alle T, Kovalevich J, Monti L, Cornec AS, Yao Y, James MJ, Trojanowski JQ, Lee VM, Smith AB 3rd, Brancale A, Brunden KR, Ballatore C
    Evaluation of the Structure-Activity Relationship of Microtubule-Targeting 1,2,4-Triazolo[1,5-a]pyrimidines Identifies New Candidates for Neurodegenerative Tauopathies.
    J Med Chem. 2021 Jan 28;64(2):1073-1102

  177. Purdy TN, Kim MC, Cullum R, Fenical W, Moore BS
    Discovery and Biosynthesis of Tetrachlorizine Reveals Enzymatic Benzylic Dehydrogenation via an ortho-Quinone Methide.
    J Am Chem Soc. 2021 Mar 17;143(10):3682-3686

  178. Tang M, Tiwari SK, Agrawal K, Tan M, Dang J, Tam T, Tian J, Wan X, Schimelman J, You S, Xia Q, Rana TM, Chen S
    Rapid 3D Bioprinting of Glioblastoma Model Mimicking Native Biophysical Heterogeneity.
    Small. 2021 Apr;17(15):e2006050

  179. Monti L, Cornec AS, Oukoloff K, Kovalevich J, Prijs K, Alle T, Brunden KR, Smith AB 3rd, El-Sakkary N, Liu LJ, Syed A, Skinner DE, Ballatore C, Caffrey CR
    Congeners Derived from Microtubule-Active Phenylpyrimidines Produce a Potent and Long-Lasting Paralysis of Schistosoma mansoni In Vitro.
    ACS Infect Dis. 2021 May 14;7(5):1089-1103

  180. Francisco KR, Varricchio C, Paniak TJ, Kozlowski MC, Brancale A, Ballatore C
    Structure property relationships of N-acylsulfonamides and related bioisosteres.
    Eur J Med Chem. 2021 Jun 5;218:113399

  181. de Rond T, Asay JE, Moore BS
    Co-occurrence of enzyme domains guides the discovery of an oxazolone synthetase.
    Nat Chem Biol. 2021 Jul;17(7):794-799

  182. Demirkiran O, Almaliti J, Leão T, Navarro G, Byrum T, Valeriote FA, Gerwick L, Gerwick WH
    Portobelamides A and B and Caciqueamide, Cytotoxic Peptidic Natural Products from a Caldora sp. Marine Cyanobacterium.
    J Nat Prod. 2021 Aug 27;84(8):2081-2093

    183. 2022

  183. Aron AT, Petras D, Schmid R, Gauglitz JM, Büttel I, Antelo L, Zhi H, Nuccio SP, Saak CC, Malarney KP, Thines E, Dutton RJ, Aluwihare LI, Raffatellu M, Dorrestein PC
    Native mass spectrometry-based metabolomics identifies metal-binding compounds.
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